The fund, pegged at Sh50 billion , targets individuals, small enterprises, chamas and table banking groups, Saccos and start-ups, among other groups.
It was one of the key campaign promises of the Ruto administration to provide financial services and products that are affordable and accessible for all.
"We walked all over the country and Kenyans told us they need funding to run their business," said Ruto during its launch in Nairobi on November 30.
"That's why we decided to create a special fund to allow all Kenyans to get affordable credit despite their lack of physical address, a title deed, log books or similar guarantees."
At the meeting, Mr Ngatia, who dropped out of the race for the Nairobi Governor's seat on a Jubilee ticket under the Azimio la Umoja banner committed to working with the ruling Kenya Kwanza administration.
The chamber has recently increased efforts to support small businesses and last week signed a partnership deal with KCB Group to support MSMEs.
Under the deal, KCB Bank will offer its products, payment and forex solutions and free account maintenance for amounts above Sh120,000 to its over 20,000 members.
At the same time, the KCB Foundation will provide MSMEs with free financial literacy programmes through the 2Jiajiri, Mifugo ni Mali and Agribusiness programmes.
Earlier, KNCCI hosted prominent United Arabs Emirates (UAE) and Somalia business leaders as it launched a new e-commerce platform www.odernget.com platform.
"Businesses should take advantage of this new platform for its ability to reduce costs of trade and get big bargains from UAE," said Ngatia.
Also at a meeting with the Japanese Ambassador to Kenya Okinawa Ken, KNCCI identified joint opportunities for businesses from both countries, including commercialisation of the outputs from key research institutions such as the Jomo Kenyatta University of Agriculture and Technology.
"We are looking to a bright prospect of 2023, especially with Covid-19 now behind us, and the future can't be brighter for small and medium businesses in Kenya," he said.